Table 5 The effects of SNP, DNA methylation, and their interactions in selected models ( GATA3 )
Effects at age 10 (n = 34) | Effects at age 18 (n = 233) | ||||||
|---|---|---|---|---|---|---|---|
Model | Model frequency# | Parameter | Estimate (log OR) | P value$ | Estimate (log OR) | P value$ | |
1 | 5 | cg13543854 | −20.27 | 0.19 | 3.21 | 0.066 | |
rs568727 | AA | NA | NA | 27.47 | 0.37 | ||
CC | 123.62 | 0.04 | −11.50 | 0.20 | |||
AC | Ref. | Ref. | Ref. | ||||
cg13543854* rs568727 | AA | NA | NA | 9.42 | 0.36 | ||
CC | 40.76 | 0.04 | −3.52 | 0.21 | |||
AC | Ref. | Ref. | |||||
2 | 27 | cg12405139 | −12.15 | 0.049 | −0.02 | 0.99 | |
rs2229359 | AG | −47.21 | 1.00 | −13.86 | 1.00 | ||
AA | NA | NA | −22.39 | 0.36 | |||
GG | Ref. | Ref. | Ref. | ||||
cg12405139* rs2229359 | AG | 12.15 | 1.00 | 0.02 | 1.00 | ||
AA | NA | NA | 8.58 | 0.37 | |||
GG | Ref. | Ref. | Ref. | ||||