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Table 3 Meta-regression analysis for the main potential interference factors with random-effects model
| Subgroup | Coefficient (95% CI) | P-value | τ2 |
|---|---|---|---|
| Sample type | -1.03 (-2.4, 0.34) | 0.14 | 0.90 |
| Age | -0.3 (-0.44, -0.16) | 2.0 × 10 -5 | 0.18 |
| Proportion of stage I | -0.01 (-0.05, 0.03) | 0.608 | 0.79 |
| Ratio of male to female | -0.69 (-8.1, 6.71) | 0.855 | 0.98 |
| Detection methods | -0.09 (-1.28, 1.1) | 0.88 | 1.11 |
| Study aim | -0.82 (-2.05, 0.41) | 0.19 | 1.07 |
| Single/Multiple targets | 1.05 (-0.71, 2.81) | 0.243 | 1.01 |
| Hetero/Autogenous control | -1.25 (-2.35, -0.15) | 0.026 | 0.89 |
| Ad2Sc | 0.44 (-0.56 , 1.44 ) | 0.387 | 0.89 |
| Primer set | -1.02 (-1.02, -2.02) | 0.05 | 0.35 |
