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Figure 3 | Clinical Epigenetics

Figure 3

From: High-throughput DNA analysis shows the importance of methylation in the control of immune inflammatory gene transcription in chronic periodontitis

Figure 3

Comparative analysis of variations in the frequency of negative probes in the groups. The position of probes in the compared groups was matched using a sliding window of 140 bases (with a shift of one base) starting at +2,000 to +1,860 (within gene) and ending at a window containing sequences from āˆ’1,860 to āˆ’2,000 (promoter). Each point represents the difference between the frequency of the negative probes between the two groups. Significant differences (Mann-Whitney test) are shown in different colors. The 5ā€² position of the window is shown by vertical dotted lines. The larger regions with significant differences were observed when subtracting values: immuneā€‰āˆ’ā€‰cell cycle (A), immuneā€‰āˆ’ā€‰stable (B), and (C) cell cycleā€‰āˆ’ā€‰stable. The x-axis positions larger than 0 represent gene bodies and less than 0 represent promoter regions.

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