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Figure 1 | Clinical Epigenetics

Figure 1

From: The effects of olanzapine on genome-wide DNA methylation in the hippocampus and cerebellum

Figure 1

Heat map of differential DNA methylation and the number of genes showing a) increased and b) decreased methylation. (A) Heat map of differential DNA methylation enrichment peaks of genes in the hippocampus, following olanzapine treatment of rats. The average normalized log2-ratio scan values were used to calculate the M' value (M' = Average(log2MeDIPE/InputE) – Average(log2MeDIPC/InputC)) for each probe. Venn diagrams depicting the number of genes that show an increase (B) or decrease (C) in methylation in brain tissues and the liver, following olanzapine treatment of rats.

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