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Table 1 Sites in the Htt protein which undergo PTMs

From: Targeting Huntington’s disease through histone deacetylases

Acetylation

 K6 (Aiken et al. 2009)

Palmitoylation

 C214 (Yanai et al. 2006)

Phosphorylation

 T3 (Aiken et al. 2009)

 S13 (Aiken et al. 2009; Thompson et al. 2009; Gu et al. 2009)

 S16 (Aiken et al. 2009; Gu et al. 2009)

 T407 (Dephoure et al. 2008)

 S413 (Dephoure et al. 2008)

 S421 (Colin et al. 2008; Humbert et al. 2002; Pardo et al. 2006; Rangone et al. 2004; Warby et al. 2009; Zala et al. 2008)

 S434 (Luo et al. 2005)

 S533 (Schilling et al. 2006)

 S535 (Schilling et al. 2006)

 S536 (Schilling et al. 2006)

 S1181 (Anne et al. 2007; Daub et al. 2008; Schilling et al. 2006)

 S1872 (Daub et al. 2008; Dephoure et al. 2008)

 S1876 (Dephoure et al. 2008; Xia et al. 2008)

 S1201 (Anne et al. 2007; Brill et al. 2009; Daub et al. 2008; Schilling et al. 2006)

 S2076 (Schilling et al. 2006)

 S2653 (Schilling et al. 2006)

 S2657 (Schilling et al. 2006)

 T2940 (Dephoure et al. 2008)

Sumoylation

 K6, K9, K15 (Steffan et al. 2004)

Ubiquitination

 K6, K9, K15 (Steffan et al. 2004)

  1. The table was generated through the use of SysPTM (http://lifecenter.sgst.cn/SysPTM; Li et al. 2009), PhosphoSitePlus® (http://www.phosphosite.org/) and literature searches