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Table 2 Immunocytochemistry results

From: 5-Aza-2′-deoxycytidine stress response and apoptosis in prostate cancer

Proteins Cells
Control (no drug treatment) 5-Aza-2′-deoxycytidine (250 nM)
PC-3 TSUPr1 DuPro PC3 TSUPr1 DuPro
Caspase-3 na +++ +++
Bcl2 nd ++ ++ na +++ +++
Bak nd na ++ ++
Bax nd na + +
Bcl-XS nd na ++ ++
DNMT1 ++ ++ ++ na +++ +++
HDAC1 ++ ++ ++ na + +
  1. +++High, ++medium, and +low expression, − no expression, nd not detected, na not applicable; PC3 cells died at very low dose (35 nM)